Cancer Chemopreventive Effect of Spirogyra Neglecta (Hassall) Kützing on Diethylnitrosamine-Induced Hepatocarcinogenesis in Rats
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چکیده
منابع مشابه
Evaluation of hepatic antioxidant capacities of Spirogyra neglecta (Hassall) Kützing in rats
Free radicals are one of the causes of chronic and degenerative diseases. Antioxidants can protect the progression of free radical mediated disorders. The aim of this study was to evaluate the antioxidant activity of Spirogyra neglecta (Hassall) Kützing in rats. The rats were divided into 5 groups. Group 1 served as control. Groups 2 and 3 were administered hot water extract of S. neglecta at 5...
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Spirogyra neglecta extract (SNE) has shown antihyperglycemia and antihyperlipidemia in type 2 diabetic mellitus (T2DM) rats. This study investigated the antioxidant and renoprotective effects of SNE in T2DM rats induced by high-fat diet with low-single dose streptozotocin. T2DM rats were fed daily with SNE (0.25, 0.5, and 1 g/kg BW) for 12 weeks. Renal morphology, malondialdehyde levels, qPCR, ...
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Liver cancer is a major chronic health problem in Sub-Saharan Africa, East Asia, and Southeast Asia. It is the third most common cancer in males and the sixth most common cancer in females in Thailand (Attasara and Buasom, 2011). The risk factors of liver cancer include hepatitis B and C, viral infection, alcohol, and chemical carcinogens such as aflatoxin B1 (Ding and Wang, 2014). Avoiding exp...
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15 صفحه اولPreventive Effect of Geraniol on Diethylnitrosamine-Induced Hepatocarcinogenesis in Rats
BACKGROUND Geraniol is a plant-derived phytochemical possessing anti-cancer action. The anti-carcinogenic effect of geraniol was investigated in the diethylnitrosamine (DEN)-induced hepatocarcinogenic rat model. METHODS Male Wistar rats were intraperitoneally injected with 300 μL of phosphate-buffered saline (PBS) (G1; n = 4) or DEN (100 mg/kg body weight) dissolved in PBS (G2; n = 8) every 2...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2014
ISSN: 1513-7368
DOI: 10.7314/apjcp.2014.15.4.1611